Browsing School of Bio-Medical Sciences (Bio-Medical) by Type
Now showing items 1-20 of 28
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Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Scientific Research Publishing, 2019)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta-lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study was ... -
Assessment of biosafety and biorisk management practices among medical laboratory students in two institutions in Uganda
(Elsevier, 2022)Medical laboratory workers handle clinical specimens, which are a threat of exposure to infectious agents. Notably, medical laboratory science students report for internships with only theoretical knowledge of biosafety ... -
Attitudes and knowledge gaps of the communities about cervical carcinoma and it’s detection in four selected districts of Uganda
(INABSTA, 2007)The main objective of the study was to determine the attitudes and knowledge gaps about cervical carcinoma in the urban and rural women and health workers. A cross sectional study survey was done on four districts of ... -
Bacteriological profle, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to afect more than 30 million people worldwide annually, potentially ... -
Clindamycin resistance among methicillin resistant staphylococcus aureus isolated from human and respective household swine in greater Kabale Region—South Western Uganda
(Scientific Research Publishing, 2019)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. Clindamycin ... -
Cotrimoxazole Prophylaxis specifically selects for Cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus with varied Polymorphisms in the target genes folA and folP
(Hindawi Publishing Corporation, International Journal of Microbiology, 2012)The selection of antibiotic resistance by cotrimoxazole prophylaxis was evaluated, and we characterized the mechanism of cotrimoxazole resistance in Streptococcus mutans and Streptococcus sobrinus. In vitro susceptibility ... -
Detection of Leishmania in human blood and tissue exudate ingested by Tunga penetrans
(International Scholars Journals, 2020-09)Communities in Uganda are experiencing a multiparasitism, blood microscopy often reveals Leishmania and microfilaria in patients with anaemia, haemorrhage and splenomegaly. Many are likely asymptomatic and probably exposed ... -
Differential prevalence of transporter polymorphisms in symptomatic and asymptomatic Falciparum Malaria Infections in Uganda
(Journal of Infectious Diseases, 2014)We explored associations between Plasmodium falciparum drug resistance–mediating polymorphisms and clinical presentations in parasitemic children enrolled in a cross-sectional survey in Tororo, Uganda, using a retrospective ... -
Diversity and distribution of Spa Types among Methicillin resistant staphylococcus aureus isolated from humans and livestock in Kabale District - South Western Uganda
(Journal of Veterinary Health Science, 2022)Background: S. aureus is a skin and mucosal bacterial commensal of both humans and animals which has evolved as an important pathogen implicated to cause various infections. High levels of antibiotic use have resulted into ... -
Elucidating emergence and transmission of multidrug-resistant tuberculosis in treatment experienced patients by whole genome sequencing
(PLOS One, 2013)Background: Understanding the emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is crucial for its control. MDR-TB in previously treated patients is generally attributed to the selection of drug resistant ... -
Exploring the causal effect of omega-3 polyunsaturated fatty acid levels on the risk of type 1 diabetes: a Mendelian randomization study
(Frontiers, 2024)The burden of Type 1 diabetes (T1D) is vast and as of 2021, an estimated 8.4 million people were living with the disease worldwide. Predictably, this number could increase to 17.4 million people by 2040. Despite nearly a ... -
Histological Demonstration of the Organisms Causing Human Tungiasis in Eastern Uganda
(Journal of Cytology & Histology, 2020)Background: Tungiasis, a neglected tropical ecto-parasitic disease, has resurged in Sub-Saharan Africa, causing public concern and at times confusing diagnosis. In October 2010, following widespread human disease within ... -
How reliable are hematological parameters in predicting uncomplicated plasmodium falciparum malaria in an Endemic Region?
(Hindawi Publishing Corporation, 2013)Background. Malaria remains endemic in Sub-Saharan Africa. Hematological changes that occur have been suggested as potential predictors of malaria. This study was aimed at evaluating the diagnostic relevance of hematological ... -
Incidence and etiology of catheter associated urinary tract infection among admitted patients at Kabale Regional Referral Hospital, South Western Uganda
(Scientific Research Publishing, 2019)Introduction: Catheter Associated Urinary Tract Infection is the most common hospital acquired infection worldwide. Urinary Tract Infections among catheterised patients are on rise regardless of antibiotic use and this is ... -
Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study
(JMIR, 2023-12)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
Investigation of a haemorrhagic febrile illness in Nakaseke District, Central Uganda: A case series report
(African Journal of Parasitology Research, 2020-02-05)Persons in Nakaseke and neighbouring districts within Central Uganda suffered from a haemorrhagic febrile illness. Four tested positive for the Crimean-Congo Haemorrhagic Fever (CCHF) virus, five for the Rift Valley Fever ... -
Levels of Bifurcation of the Sciatic Nerve among Ugandans at School of Biomedical Sciences Makerere and Mulago Hospital Uganda
(East and Central African Journal of Surgery, 2010)Background: The sciatic nerve is derived from the lumbo-sacral plexus, It is the thickest nerve in the whole body, it exits the gluteal region through the lower part of the greater sciatic foramen, it is the main innervator ... -
Meta-analysis to compare the accuracy of GeneXpert, MODS and the WHO 2007 algorithm for diagnosis of smear-negative pulmonary tuberculosis
(BMC Infectious Diseases, 2013)Background: Smear-negative pulmonary tuberculosis (SN-PTB), which is common in HIV-infected patients, is difficult to diagnose using smear microscopy alone. In 2007, the WHO developed an algorithm to improve the diagnosis ... -
A metabolic biosignature of early response to anti-tuberculosis treatment
(BMC Infectious Diseases, 2014)Background: The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacterium ... -
Musculoskeletal disorder risk factors among nursing professionals in low resource settings: a cross-sectional study in Uganda.
(BMC Nursing, 2014)Background: Musculoskeletal disorders (MSD) constitute one of the main occupational hazards among health care workers. However, few epidemiological studies on work related MSD among nursing professionals have been carried ...