Browsing School of Bio-Medical Sciences (Bio-Medical) by Type
Now showing items 1-20 of 252
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Abdominal sonographic changes among HIV-TB co-infected adult patients initiating highly active antiretroviral therapy at Mulago Hospital Complex.
(Makerere University, 2014)Human immunodeficiency virus (HIV) infection increases the risk for infection with Mycobacterium tuberculosis (TB). In HIV-TB co-infected patients, abdominal tuberculosis accounts for 11-16% of extra pulmonary cases. ... -
Activity and dermal safety of Citrus limon (L.) Burm. f oil from Soroti, Uganda against selected Gram positive and Gram-negative bacteria.
(Makerere University, 2018-08-02)Background: Essential oils are widely used for culinary and nonculinary purposes like nutraceuticals, traditional medicine, aromatherapy and cosmetics. Genus citrus of the Rutaceae family has several plants including Citrus ... -
African human variants that potentially impact the outcome of SARS-CoV-2 infection
(Makerere University, 2023-11-15)Introduction: The SARS-CoV-2 pandemic has had an unprecedented global impact, resulting in millions of confirmed cases and deaths. However, the severity and death rates varied among different ethnicities and geographical ... -
Anatomical Variations of Gall bladder and Bile ducts-An MRI study
(Makerere University, 2023-11-04)Introduction: The Anatomy of the biliary tree is complex and is characterized by the frequent presence of Anatomical variations which can be found in ~50% of the general population. Accurate knowledge of the bile duct ... -
Anti-mycobacterial activity and acute toxicity of Erythrina abyssinica, Cryptolepis sanguinolenta and Solanum incanum
(Makerere University, 2010-10)Tuberculosis (TB) kills approximately two million people annually. Efforts to treat the disease have been made much more difficult due to development of drug resistant TB strains (MDR and XDR TB) and co-infection with HIV ... -
Antibody responses to Mycobacterial glycans and glycolipids as potential correlates of protection from mycobacterium tuberculosis infection in BCG vaccinated children
(Makerere University, 2021-04-01)Background: Globally, tuberculosis (TB) has remained the main cause of death from a single infectious pathogen. The only licensed TB vaccine to date, BCG, has variable efficacy. We need to understand the mechanism ... -
Antimicrobial stewardship practices and quality of antibacterial use in children under five and women in labour with obstetric risk factors in selected health facilities in Uganda
(Makerere University, 2024)Introduction Bacterial infections are a leading cause of morbidity and mortality in Ugandan hospitalised children under the age of five. Disparities exist in using antibacterial agents to treat bacterial infections at ... -
Antimicrobial Susceptibility and Plasmid Genes Conferring Multi-Drug Resistance among Klebsiella Pneumoniae Isolated from patients attending Mulago National Referral Hospital from 2017 to 2018.
(Makerere University, 2019-11-25)Introduction: Antimicrobial Resistance results from exposure of microorganisms to antimicrobial substances, consequently with the ineffectiveness of treatments and exacerbating the risk of spread to others. Klebsiella ... -
Antimicrobial Susceptibility of 3rd Generation Cephalosporins-Resistant Escherichia coli, Klebsiella pneumoniae and Enterobacter spp Isolates Carried in the Gut of Patients on admission to Mulago Hospital.
(2019-11-20)Background: Resistance to 3rd and 4th generation cephalosporin is on an increase worldwide. These cephalosporins are used in management of severe infections caused by Enterobacteriaceae. The main objective of the study was ... -
Antinociceptive activity and acute toxicity profile of Leucus calostachys olive in animal models
(Makerere university, 2024-11)Pain remains a cardinal sign and symptom for most diseases and a major reason for patients visiting healthcare providers. Conventional treatment modalities do not adequately address pain, and as a result, most local ... -
Artemether-Lumefantrine Plasmodium Falciparum clearance and associated factors among uncomplicated Malaria patients in Adjumani District, Uganda
(Makerere University, 2023)The development of artemisinin resistance threatens the efforts to global malaria control. Artemisinin resistance has been reported in Northern Uganda and some African countries. Considering both host and parasite genetic ... -
Aspergillus sensitisation and asthma in Uganda
(Makerere University, 2022-10-31)Background: Asthma is one of the neglected diseases in Africa and occurs at a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. Aspergillus fumigatus ... -
Assessment of microbiological quality of herbal preparations used in the treatment of malaria, cough and HIV in Kampala district
(Makerere University, 2022-02)In Uganda, herbal medicine is widely used in the treatment and prevention of various conditions including cough, malaria and HIV opportunistic infections. The demand for herbal products has increased among many consumers ... -
Assessment of quality of raw bovine milk sold in Kampala City: A cross sectional study
(Makerere University, 2021-03)Background: Recently there has been increasing reports concerning the safety of certain foods consumed in Uganda. Milk and meat sold on the Ugandan market have been reported to be contaminated with chemicals or adulterants ... -
AN ASSESSMENT OF UNDERSTANDING OF INFORMATION PROVIDED IN GENETIC RESEARCH AMONG PEOPLE LIVING WITH HIV AT THE INFECTIOUS DISEASES INSTITUTE (IDI)
(Makerere University, 2019-07)Introduction Obtaining informed consent is essential for biomedical research; and for informed consent to be valid, it is imperative that participants understand all the information disclosed to them before making voluntary ... -
Association of Carbapenemase Genes with Phenotypic Resistance to Carbapenems among Gram Negative Bacteria
(Winnie Binoga, 2019-12-05)BACKGROUND: Carbapenem drugs are the last resort antibacterial agents used in the treatment of Extended Spectrum Beta-Lactamase multi drug resistant Gram negative bacterial infections. Resistance to these drugs is reported ... -
Asymptomatic Bacteriuria in Diabetic patients attending Mulago Hospital
(Makerere University, 2010-08)Introduction There are about 285 million people currently living with Diabetes Mellitus (DM) and the number is expected to reach 438 million in 2030. Intensive management of DM reduces microvascular complications by about ... -
Attitudes and practices of herbalists towards the informed consent process
(Makerere University, 2022)Introduction: Informed Consent (IC) is a major cornerstone in medical ethics that is expected to be implemented universally in healthcare. The growing use of herbal medicines in developing countries has aroused concerns, ... -
Autopsy survey of histopathological features and immunohistochemical markers of dementia in medico-legal deaths at Mulago hospital and KCCA mortuaries, Uganda
(Makerere University, 2022-11-22)Background: Dementia is a neurodegenerative disorder characterized by an irreversible cognitive decline. Although previously associated with old age, in people aged 65 and above, recent studies have reported early-onset ... -
Awareness and perception of patients rights in clinical services among clients attending the outpatients department at Mawenzi Regional Referral Hospital, Tanzania
(Makerere University, 2023-10)Background: Patient rights are those owed to the patient as a human being, by physicians, healthcare workers, and by the state. Without the appropriate understanding of the patient’s rights, the healthcare team may at times ...