School of Bio-Medical Sciences (Bio-Medical): Recent submissions
Now showing items 21-40 of 397
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Determination of Anti-HBsAg antibody titers among children under five years who received Hepatitis B vaccine under UNEPI in Kawempe Division, Kampala-Uganda
(Makerere University, 2024)Background: Hepatitis B Virus is a global health threat with estimated 257 million people chronically infected with the infection (WHO 2017). HBsAg sero prevalence is approximately 3.6% with high endemicity observed in ... -
Experiences and ethical issues during shared decision-making in rural healthcare: A case of Budumba and Butaleja HC III, Uganda
(Makerere University, 2024)Background: Shared decision-making (SDM) in healthcare is a collaborative process where patients are supported to make informed decisions according to their preferences. Healthcare decisions affect patients' lives which ... -
Describing immune responses to SARS-CoV-2 in natural infection and among vaccine Recipients in Uganda
(MAKERERE UNIVERSITY, 2023-12-04)Background: Describing T and B cell immune responses to SARS-COV-2 among naturally infected and vaccinated individuals is of at most importance in developing vaccines that will lead to COVID-19 disease resolution. Here we ... -
Researcher's perspectives and practices for sharing clinical data in international collaborative research
(Makerere University, 2023)Background: Data sharing is an important requirement for effective and efficient research, particularly biomedical research. It has however not yet been widely adopted by the clinical research community. In Uganda, little ... -
Health workers’ perceptions and ethical issues faced in the delivery of contraceptives to adolescents at selected Public health facilities in Kampala
(Makerere University, 2023-10)Introduction: Adolescent pregnancy and subsequent childbirth among women less than 18 years old continues to be a major global public health concern, affecting more than 16 million girls and young women worldwide. Uganda ... -
Identification and management of perceived researcher vulnerability at Makerere College of Health Sciences
(Makerere University, 2023-07-23)Usually, the concept of and worry about vulnerability in research is treated almost exclusively as applicable to research participants, and very little consideration, if any, is given to researchers. This bias is even ... -
p53 protein expression in epithelial ovarian cancer and it is association with clinicopathological features as seen in selected histopathology laboratories in Kampala
(Makerere University, 2024)Background: Globally, cancer of the ovary is the 7th most frequently diagnosed among women. The majority of the women in low- and middle-income countries (LMICs) are diagnosed at a late stage that is untreatable leading ... -
Perceptions and experiences of plagiarism among graduate students at Makerere University College of Health Sciences
(Makerere University, 2023)Introduction: Plagiarism is a global challenge in academia and in most scholarly work. In recent years, many countries have come up with policies, both legal and institutional, to mitigate it. In Uganda, graduate students ... -
VEGF protein expression in oesophageal cancer and associated clinicopathological and demographic features as seen at the Department of Pathology, Makerere University
(Makerere University, 2024)In 2020, esophageal cancer was the 10th most common cancer worldwide with an estimated 604,100 new cases and the sixth leading cause of cancer death with 544,076 deaths associated with it. Esophageal squamous cell carcinoma ... -
Exploring the causal effect of omega-3 polyunsaturated fatty acid levels on the risk of type 1 diabetes: a Mendelian randomization study
(Frontiers, 2024)The burden of Type 1 diabetes (T1D) is vast and as of 2021, an estimated 8.4 million people were living with the disease worldwide. Predictably, this number could increase to 17.4 million people by 2040. Despite nearly a ... -
Carbapenem resistance among gram negative rods isolated from surgical site infections at Mulago and Kawempe National referral hospitals
(Makerere University, 2024-01-04)Background: Surgical site infections are becoming increasingly difficult to manage with the rise of drug resistance among causative bacteria. Contributing to this, the use of foreign implants in certain surgeries pauses ... -
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus Aureus Among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Archives of Clinical and Medical Microbiology, 2023-10-24)Background Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Scientific Research Publishing, 2019)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta-lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study was ... -
Bacteriological profle, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to afect more than 30 million people worldwide annually, potentially ... -
Assessment of biosafety and biorisk management practices among medical laboratory students in two institutions in Uganda
(Elsevier, 2022)Medical laboratory workers handle clinical specimens, which are a threat of exposure to infectious agents. Notably, medical laboratory science students report for internships with only theoretical knowledge of biosafety ... -
Status of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara University Teaching Hospital in Southwestern Uganda
(Therapeutic advances in infectious disease, 2021)Background: Pulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less ... -
Investigating Metabolic and Molecular Ecological Evolution of Opportunistic Pulmonary Fungal Coinfections: Protocol for a Laboratory-Based Cross-Sectional Study
(JMIR, 2023-12)Background: Fungal-bacterial cocolonization and coinfections pose an emerging challenge among patients suspected of having pulmonary tuberculosis (PTB); however, the underlying pathogenic mechanisms and microbiome ... -
Plasmodium falciparum genetic diversity and multiplicity of infection based on msp‑1, msp‑2, glurp and microsatellite genetic markers in Sub-Saharan Africa: a systematic review and meta-analysis
(BMC, 2024)Background In sub-Saharan Africa (SSA), Plasmodium falciparum causes most of the malaria cases. Despite its crucial roles in disease severity and drug resistance, comprehensive data on Plasmodium falciparum genetic ... -
A comparison of frequencies and function of myeloid derived suppressor cells (MDSCS) IN TB/HIV co-infected and HIV mono-infected individuals in Uganda
(Makerere University, 2023)Background Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. These cells negatively regulate the immune function either by arginine ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba Sub-county, Kamwenge District, Southwestern Uganda, August–September 2018
(BMC, 2024)Objective Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated ...