College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3391
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An observational study in an urban Ugandan clinic comparing virological outcomes of patients switched from first-line antiretroviral regimens to second-line regimens containing ritonavir-boosted atazanavir or ritonavir-boosted lopinavir
(BMC, 2019)Background: The World Health Organisation approved boosted atazanavir as a preferred second line protease inhibitor in 2010. This is as an alternative to the current boosted lopinavir. Atazanavir has a lower genetic barrier ... -
Understanding the barriers and facilitators of COVID-19 risk mitigation strategy adoption and COVID-19 vaccination in refugee settlements in Uganda: a qualitative study
(BMC, 2023)Background: Perspectives on COVID-19 risk and the willingness and ability of persons living in refugee settlements to adopt COVID-19 prevention strategies have not been rigorously evaluated. The realities of living conditions ... -
One-year survival and prognosticators of adults with acute leukemia at the Uganda Cancer Institute
(American Society of Clinical Oncology, 2023)Purpose: Acute leukemias are associated with substantial morbidity and mortality, particularly in the adult population. Despite an increasing burden of acute leukemia in developing countries, there are limited data on ... -
Prevalence and factors associated with intimate partner violence among women attending antenatal care at Kawempe National Referral Hospital
(Makerere University, 2025-04-16)Background: Intimate partner violence (IPV) against pregnant women remains a major public health problem in Africa and worldwide. IPV during pregnancy is an important risk factor for adverse health outcomes to women and ... -
Sex and HIV differences in Preserved Ratio Impaired Spirometry (PRISm) among Ugandans postpneumonia
(Oxford Academic, 2024)Background: Preserved ratio impaired spirometry (PRISm), defined as a normal ratio of forced expiratory volume in 1 second (FEV1) to forced vital capacity (≥0.70) with low FEV1 (<80% predicted), has been associated with ... -
The burden of severe asthma in sub-Saharan Africa: Findings from the African Severe Asthma Project
(Elsevier, 2024)Background: Severe asthma is associated with high morbidity, mortality, and health care utilization, but its burden in Africa is unknown. Objective: We sought to determine the burden (prevalence, mortality, and activity ... -
Patient level barriers to accessing TB care services during the COVID-19 pandemic in Uganda, a mixed methods study
(BMC, 2024)Introduction Lockdown measure has been utilized widely to mitigate COVID-19 pandemic transmission and recently during the 2022 Sudan Ebola Virus Disease outbreak in Uganda. These have setback effects on the continuity of ... -
Tuberculosis and diabetes mellitus comorbidity in an adult Ugandan population
(BMC, 2024)Background Diabetes mellitus (DM) has a direct impact on the clinical manifestation and prognosis of active tuberculosis disease (TB) and is known to increase the chance of developing the condition. We sought to determine ... -
Decision to delivery interval and associated factors among Lucas category 1 caeserean indications in Kawempe National Referral Hospital
(Makerere University, 2025)Background: Emergency caesareans often face delays to start in developing countries like Uganda. This leads to maternal and neonatal morbidity and mortality rates to be much higher in developing countries than in developed ... -
Missed opportunities for administration of low-dose aspirin to pregnant women at high risk of preeclampsia at Kawempe National Referral Hospital
(Makerere University, 2025)Background: Evidence suggests low-dose aspirin (LDA) prophylaxis given between 11-16 weeks of gestation and stopped at 36 weeks may prevent or delay early onset preeclampsia in high-risk individuals and may reduce maternal ... -
Short-term side effects of chemoradiation and quality of life among women receiving chemoradiotherapy for locally advanced cervical cancer at Uganda Cancer Institute
(Makerere University, 2025)Background: This study identified the types and prevalence of short-term side effects of chemoradiation and how they affect the quality of life of patients with cervical cancer. Cervical cancer is the leading cause of ... -
Blood pressure control and associated factors among patients with type 2 diabetes mellitus and hypertension in Tororo hospital
(Makerere University, 2022)Introduction: The co – existence of hypertension and type 2 diabetes mellitus (T2DM) increases the risk of cardiovascular disease (CVD), nephropathy, retinopathy and dyslipidemia. In sub Saharan Africa, it was predicted ... -
Factors associated with delay in seeking care for children under five years diagnosed with malaria attending Tororo General Hospital
(Makerere University, 2024)Background: In children, ability to diagnose malaria early and initiating treatment on time have been registered as a successful pathway towards controlling the malaria infection. This pathway breaks the chain of disease ... -
Factors influencing COVID-19 vaccine uptake among pregnant women aged 18 - 45 attending antenatal care in Nakivale Refugee Settlement, Isingiro District – Uganda
(Makerere University, 2024)Background: The COVID-19 pandemic has necessitated global vaccination efforts, with particular attention to vulnerable populations, including pregnant women (Amimo, Lambert, Magit, & Hashizume, 2021). Despite these efforts, ... -
Assessing readiness for provision of online pharmaceutical services by retail pharmacies in Greater Kampala Metropolitan, Uganda
(Makerere University, 2024)Introduction: The first online pharmacy, Soma (www.soma.com), started in the United States in January 1999. More than two decades later, the industry has transformed due to the rise of online shopping, electronic health ... -
Modern contraceptive use among teenage mothers aged 13-19 years in Kamuli District Uganda
(Makerere University, 2024)Background: In Uganda, almost a quarter (24%) of women have given birth by the age of 19, making it the highest teenage pregnancy rate in East Africa. Teenage mothers often face adverse outcomes such as school dropout, ... -
The prevalence and spectrum of brain MRI findings among children with developmental delay at selected hospitals in Kampala
(Makerere University, 2025-06-17)Background: Developmental delay denotes significant delay in one or more developmental domains. In children ages 3–17 years, the global burden of developmental delay is ~1 to 3%. Brain Magnetic Resonance Imaging (MRI) ... -
Level of job satisfaction and associated factors among health workers in hospitals in Mbarara District
(Makerere University, 2021)Background: The effectiveness of health care delivery systems is largely dependent on the commitment of human resources available to respond to the health needs of populations. However, job satisfaction among health ... -
Predictors of a positive prostate biopsy following PSA testing: a retrospective study of Ugandan men aged 40 or more years presenting to the Uganda Cancer Institute for prostate-related care between 2014 - 2021.
(Makerere University, 2025-06-20)Introduction: The incidence and mortality due to prostate cancer (PCa) have been rising globally, making it the second most commonly diagnosed malignancy among men and the fourth most common cancer overall. In Uganda, PCa ... -
Determining the factors contributing to real-time ARV Stock Status (RASS) data quality and reporting rate in West Acholi sub-region, Uganda
(Makerere University, 2024)Introduction: The World Health Organization aims for universal HIV control by 2030, requiring robust healthcare infrastructure and efficient supply chain management. In Uganda, a functional real-time ARV Stock Status (RASS) ...