College of Health Sciences (CHS): Recent submissions
Now showing items 21-40 of 3359
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Metabolic syndrome and 10-year cardiovascular risk among HIV-positive and HIV-negative adults: A cross-sectional study
(Wolters Kluwer, 2020)To determine the prevalence and correlates of metabolic syndrome (MetS) and compare 10-year cardiovascular disease (CVD) risk among Kenyan adults with and without HIV infection.We conducted a cross-sectional study among ... -
Intimate partner violence and self-reported pre-exposure prophylaxis interruptions among HIV-negative partners in HIV serodiscordant couples in Kenya and Uganda
(Lippincott, 2018)Background: Oral pre-exposure prophylaxis (PrEP) is effective for HIV prevention, and PrEP delivery studies are investigating ways to deliver PrEP with high adherence. However, in many settings with high HIV burden, intimate ... -
Tuberculosis preventive therapy (TPT) to prevent tuberculosis co-infection among adults with HIV-associated cryptococcal meningitis: A clinician's perspective
(Elsevier, 2020)As part of the END TB strategy, the World Health organization (WHO) recommends provision of tuberculosis preventive therapy (TPT) to all people at high risk of developing active TB disease. Patients with HIV-associated ... -
Prevalence and nature of potential drug-drug interactions among hospitalized HIV patients presenting with suspected meningitis in Uganda
(BMC, 2020)Background: Management of co-infections including cryptococcal meningitis, tuberculosis and other opportunistic infections in persons living with HIV can lead to complex polypharmacotherapy and increased susceptibility to ... -
Prevalence and associated factors of erectile dysfunction among men attending the urology clinic at Mulago Hospital: a cross-sectional study
(Makerere University, 2025)Background: Erectile dysfunction (ED) is a significant public health concern affecting men’s quality of life and relationships. Despite its global burden, epidemiological data on ED in Uganda, particularly among men seeking ... -
Prevalence and factors associated with Hypovitaminosis D among patients with colorectal cancer in Mulago National Referral Hospital and Uganda Cancer Institute (Uganda): A cross-sectional study
(Makerere University, 2025)Introduction: The burden of colorectal cancer has increased in Uganda. Vitamin D has immunomodulatory effects that are not only protective against malignancies such as colorectal cancer but are also associated with reduced ... -
Prevalence and factors associated with shunt survival among hydrocephalus patients that underwent ventriculoperitoneal shunt surgery at Mulago National Referral Hospital: a retrospective cross-sectional study
(Makerere university, 2025-05)Introduction: Ventriculoperitoneal shunt (VPS) surgery is one of the mainstay treatments for hydrocephalus patients. Some patients that undergo ventriculoperitoneal shunt surgery experience eventful survival. However, ... -
Prevalence of needlestick injuries and factors associated with access of PEP among health workers at casualty Mulago National Referral Hospital-a cross sectional study
(Makerere University, 2025)Background: Needle stick injuries (NSI) are accidental skin-penetrating puncture wounds from a hollow- bore needle containing another person's blood or body fluid. They are a very prevalent challenge among health workers ... -
Prevalence and factors associated with clinical outcomes among patients hospitalized with chronic obstructive lung disease on the pulmonology wards at Kiruddu and Mulago National Referral Hospital.
(Makerere University, 2024)Background: COPD is a chronic airway disease condition currently on the rise in many low middle-income countries (LMICs). This is attributed to poorly treated TB, asthma, cigarette smoking and air pollution among others. ... -
Predictors of mortality among severe traumatic brain injury patients admitted at Mulago Hospital. A retrospective cross-sectional study
(Makerere University, 2025)Introduction Severe traumatic brain injury (STBI) contributes significantly to death and disability especially in low and middle income countries. However, little is known about the mortality rate and its predictors ... -
Knowledge, attitudes and practices regarding infection prevention and control among non-medical handlers of healthcare waste in public healthcare facilities in Wakiso district.
(2024-11-13)Background: Healthcare waste can result in exposure to infectious conditions. Therefore, medical waste handlers need to adhere to infection prevention and control. Waste handlers, especially the non-medical ones, play a ... -
Genetic variation that determines TAPBP expression levels associates with the course of malaria in an HLA allotype-dependent manner
(PNAS, 2022)HLA class I (HLA-I) allotypes vary widely in their dependence on tapasin (TAPBP), an integral component of the peptide-loading complex, to present peptides on the cell surface. We identified two single-nucleotide polymorphisms ... -
Sticks and wheelchairs for elderly people in central Uganda: values of utility, provenance and presentation
(Cambridge University Press, 2022)While mobility-assistive devices ease movement and independence of persons with disabilities, their use may depend on their social and symbolic meaning. This article departs from our observation that elderly people in ... -
High viral suppression and low attrition in healthy HIV-infected patients initiated on ART with CD4 above 500 cells/μL in a program setting in Uganda
(African Health Sciences, 2020)Background: The World Health Organization recommends antiretroviral therapy (ART) for all HIV-infected patients at all CD4 counts. However, there are concerns that asymptomatic patients may have poorer viral suppression ... -
Prevalence, associated factors and in-hospital outcomes of gastrointestinal perforations at Bwera General Hospital, Kasese - Uganda: a retrospective cross-sectional study
(Makerere University, 2025)Introduction: Gastrointestinal perforations (GIPs) constitute surgical emergencies which necessitate prompt diagnosis and management that is significantly facilitated by the availability of adequate facilities and resources. ... -
Indications, early complications, and the associated factors following open surgical gastrostomy in patients admitted to Mulago National Referral Hospital
(Makerere University, 2025)Background: Feeding gastrostomy, whether performed surgically or via percutaneous endoscopic or radiological methods, is the preferred approach for long-term enteral feeding in patients who are unable to swallow but possess ... -
Accuracy of ganga hospital open injury score in predicting amputation of severe open lower limb injuries among adults seen at Mulago Hospital
(Makerere University, 2025)Background: With the recent advent of more motorization in Uganda, severe open lower limb injuries are pretty common. Hence, a frequent ethical and medical-legal dilemma in decision-making by frontline clinicians often ... -
Research priorities to inform “Treat All” policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA)
(Wiley Online Library, 2019)Introduction “Treat All” – the treatment of all people with HIV, irrespective of disease stage or CD4 cell count – represents a paradigm shift in HIV care that has the potential to end AIDS as a public health threat. With ... -
Prevalence and patterns of humeral fractures amongst patients presenting with upper limb fractures to Mulago National Referral Hospital.
(Makerere University, 2025)Introduction: Humeral fractures are some of the major orthopaedic injuries presenting to the Accident and Emergency unit among patients with musculoskeletal trauma. However, their true prevalence and patterns is not yet ... -
Diagnostic accuracy of the modified triple test in evaluation of palpable breast masses among women under 40 years attending Mulago Hospital
(Makerere University, 2025)Background: Breast lumps remain the commonest presentation among women at outpatient clinics in Uganda. However, the diagnostic utility of the modified triple test, MTT (physical breast examination, breast ultrasound, ...