College of Health Sciences (CHS): Recent submissions
Now showing items 1-20 of 3359
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The prevalence and factors associated with depression among undergraduates at Makerere University who have experienced intimate partner violence
(Makerere University, 2025)Background: Depression among university students is a growing public health concern, particularly in those who have experienced intimate partner violence (IPV). Understanding the prevalence and associated factors is crucial ... -
Career development for infection and immunity research in Uganda: a decade of experience from the Makerere University - Uganda Virus Research Institute research and training programme
(African Academy of Science, 2020)Background: The Makerere University/Uganda Virus Research Institute (UVRI) Centre of Excellence for Infection & Immunity Research and Training (MUII) is a collaborative programme supporting excellence in Infection and ... -
Intention to use immediate postpartum contraception and associated factors amongst mothers delivering from Kisenyi and Kawaala HC IVs
(Makerere University, 2025)Background:. The global prevalence of unintended pregnancies is about 41%, and 40% in low and middle-income countries. A study in Yumbe district indicated the prevalence of short birth intervals of 52.4%, from which 12% ... -
Frequency, course, outcomes and factors associated with delirium among adult patients admitted to Uganda Cancer Institute
(Makerere University, 2025)Background: Delirium is a neurocognitive disorder that commonly affects patients with cancer. Among patients with cancer admitted to oncology units, the prevalence varies from 18% to 33% and the incidence varies from 3.5% ... -
The Clinical Presentation and Factors Associatedwith Disease Severity of Rheumatoid Arthritis inUganda: A Cross-Sectional Study
(2022)Background Rheumatoid arthritis (RA) is a chronic, debilitating disease that leads to joint destruction and disability if left untreated. Few studies on RA have been conducted in Uganda, and there is limited information ... -
Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda
(PloS ONE, 2022)In Uganda, Artemether-Lumefantrine and Artesunate are recommended for uncomplicated and severe malaria respectively, but are currently threatened by parasite resistance. Genetic and epigenetic factors play a role in ... -
Identification of pathogen genomic differences that impact human immune response and disease during cryptococcus neoformans infection
(American Society for Microbiology, 2019)Patient outcomes during infection are due to a complex interplay between the quality of medical care, host immunity factors, and the infecting pathogen’s characteristics. To probe the influence of pathogen genotype on human ... -
Assessment of parasite clearance following treatment of severe malaria with intravenous artesunate in Ugandan children enrolled in a randomized controlled clinical trial
(BMC, 2018)Background Malaria control largely depends on availability of highly efficacious drugs, however, over the years, has been threatened by emergence of drug resistance. It is, therefore, important to monitor the impact of ... -
Contrasting impact of rural, versus urban, living on glucose metabolism and blood pressure in Uganda
(Wellcome Open research, 2020)Background: The burden of cardiometabolic diseases, including cardiovascular diseases and diabetes, is increasing in sub-Saharan Africa and this has been linked to urbanisation. Helminths, through their immunomodulatory ... -
Defining gaps in pre-exposure prophylaxis delivery for pregnant and post-partum women in high-burden settings using an implementation science framework
(Elsevier, 2020)Pregnancy is a high-risk period for HIV acquisition in African women, and pregnant women who become acutely infected with HIV account for up to a third of vertical HIV transmission cases in African settings. To protect ... -
Sustained positive impact on tuberculosis treatment outcomes of TB-HIV integrated care in Uganda
(The Union, 2019)OBJECTIVE: To examine tuberculosis (TB) treatment outcomes from a long-term TB-HIV (human immunodeficiency virus) integrated model of care at the Infectious Diseases Institute Clinic, Kampala, Uganda. METHODS: We included ... -
Performance of lipoarabinomannan assay using cerebrospinal fluid for the diagnosis of tuberculous meningitis among HIV patients
(Wellcome Open Research, 2019)Background: The diagnostic utility of the Mycobacteria tuberculosis lipoarabinomannan (TB-LAM) antigen lateral flow assay on cerebrospinal fluid (CSF) for the diagnosis of tuberculous meningitis (TBM) has not been extensively ... -
A public health approach to cervical cancer screening in Africa through community-based self-administered HPV testing and mobile treatment provision
(Wiley, 2020)The World Health Organization (WHO) refers to cervical cancer as a public health problem, and sub-Saharan Africa bears the world's highest incidence. In the realm of screening, simplified WHO recommendations for low-resource ... -
Castelnuovo, B. et al. (2018). Antiretroviral treatment Long-Term (ALT) cohort: a prospective cohort of 10 years of ART-experienced patients in Uganda
(BMJ, 2018)Purpose Little information is available on patients on antiretroviral treatment (ART) after a long-term period from sub-Saharan Africa, with the longest follow-up and related outcomes being after 10 years on ART. At the ... -
A Prospective Evaluation of a multisite Cryptococcal Screening and Treatment program in HIV clinics in Uganda
(Lippincott, 2018)Background—Cryptococcus is a leading cause of AIDS-related mortality. Cryptococcal antigen (CrAg) is detectable in blood before meningitis onset, and predicts death. CrAg screening amongst those with advanced HIV, and ... -
Adolescent pregnancy at antiretroviral therapy (ART) initiation: a critical barrier to retention on ART
(Wiley Online Library, 2018)Introduction: Adolescence and pregnancy are potential risk factors for loss to follow-up (LTFU) while on antiretroviral therapy (ART). We compared adolescent and adult LTFU after ART initiation to quantify the impact of ... -
Issues with measuring hepatitis prevalence in resource-limited settings
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Molecular tests expedite the diagnosis of multidrug-resistant tuberculosis in childhood
(Academia.edu, 2018)The diagnosis of paediatric tuberculosis (TB) is difficult, partly due to the low accuracy of traditional tests. Molecular TB tests can diagnose presumptive TB and drug-resistant TB (DR-TB) rapidly and may guide crucial ... -
Risk factors for and types of oesophageal cancer
(The Lancet, 2004) -
Characteristics and outcomes of admitted patients infected with SARS-CoV-2 in Uganda
(BMJ, 2020)Rationale: Detailed data on the characteristics and outcomes of patients with COVID-19 in sub-Saharan Africa are limited. Objective: We determined the clinical characteristics and treatment outcomes of patients diagnosed ...